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Liquid chromatography-mass spectrometry (LC-MS) is a technique borrowed from analytical chemistry that amalgamates the proficiency of both the Liquid Chromatography (LC) and Mass Spectrometry (MS). It combines the physical separation capabilities of LC with the mass analysis capabilities of MS. These tests are the laboratory techniques for identification, quantization and mass analysis of materials. Currently, liquid chromatography mass spectrometers (LC-MS) are increasingly being used in a wide range of fields, such as pharmaceuticals, environment, foods, and industrial materials.