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The availability of reliable methods in terms of their analytical and diagnostic characteristics is a key requirement to guarantee an efficient neonatal detection of any screenable disorder. Moreover, automation feasibility, high throughput and low costs are additional but very important features th...
Read moreGlucose 6 phosphate dehydrogenase (G6PD) deficiency remains the most prevalent enzyme dificiency in the world. It is estimated that nearly 330 million people may be affected by G6PD deficiency worldwide with a global prevalence of 4.9%. The overall incedence of G6PD deficiency in Malaysia were 5.3% ...
Read moreThe inclusion of urea cycle disorders (UCD) detection into newborn screening (NBS) is highly desirable; however, it is hampered by the lack of a specific marker for most of these disorders (exceptions to this are citrulline and argininosuccinate for detection of citrullinemia and argininosuccinic ac...
Read moreNewborn screening, in most countries, is highly centralized, with daily sample loads of 300 to over 2000 in a few cases. Therefore, totally automated systems are highly desirable. The main advantage of these systems is less hands-on-time for laboratory personnel, better traceability of the working s...
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