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Labsystems Diagnostics introduced world's first fluorometric microplate based assay for screening Phenyl Alanine in newborns to detect Phenylketonuria (PKU) and now on tandem MS along with more than 50 disorders. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) increased the screening possibilities by monitoring levels of amino acids and acylacarnitines. These tests can also be used in screening positive samples as a second tier confirmation test to differentiate between true and false positive samples. LC-MS/MS can detect several disorders with a single injection, which is important in high throughput labs.
NeoMass AAAC is used with Tandem Mass Spectrometry to detect concentrations of amino acid, free carnitine, acylcarnitines, succinylacetone and argininosuccinic acid.
The NeoMass AAAC 3.0 is an upgraded version of the NeoMass AAAC Plus kit. With no changes to the extraction process, the addition of Nucleoside and Lysophospholipid in the updated marker panel detects adenosine deaminase (ADA) deficiency and X-linked adrenoleukodystrophy (X-ALD) genetic disorders with higher sensitivity and specificity.
Expanded newborn screening panel for quantitative determination of 15 Amino acids, free Carnitines, 12 Acylcarnitines, Argininosuccinic acid (ASA) and Succinylacetone (SUAC) under the same extraction method and single injection/single run step without using any toxic compounds, on Tandem MS
Second Tier LC-MS/MS Kit for Confirmation of Congenital Adrenal Hyperplasia from Dried Blood Spots